C49
Header — not billableMalignant neoplasm of other connective and soft tissue
The ICD-10 code for malignant neoplasm of other connective and soft tissue is C49.
C49 is a non-billable header code. It groups related conditions but cannot be used on its own for reimbursement — select one of the 10 more specific codes below.
Clinical notes
Excludes1 (not coded here)
An Excludes1 note is a pure exclusion: the excluded condition and this code should never be reported together, because the two conditions cannot occur at the same time (e.g. a congenital form vs. an acquired form of the same disease).
Excludes2 (not included here)
An Excludes2 note means the excluded condition is not part of this one, but a patient can have both at the same time — in that case both codes may be reported together.
- Kaposi's sarcoma of soft tissue (C46.1)
- malignant neoplasm of heart (C38.0)
- malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
- malignant neoplasm of peritoneum (C48.2)
- malignant neoplasm of retroperitoneum (C48.0)
- malignant neoplasm of uterine ligament (C57.3)
- mesothelioma (C45.-)
Includes
Terms listed here further define or give examples of the conditions grouped under this code — they describe what the code covers, not a separate diagnosis.
- malignant neoplasm of blood vessel
- malignant neoplasm of bursa
- malignant neoplasm of cartilage
- malignant neoplasm of fascia
- malignant neoplasm of fat
- malignant neoplasm of ligament, except uterine
- malignant neoplasm of lymphatic vessel
- malignant neoplasm of muscle
- malignant neoplasm of synovia
- malignant neoplasm of tendon (sheath)
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •This is a non-billable header code. Documentation must support a more specific child code before this diagnosis can be reported on a claim.
- •Confirm the excluded condition(s) listed above are not also present — Excludes1 conditions cannot be coded together with this one.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Child codes under C49
- C49.0Malignant neoplasm of connective and soft tissue of head, face and neck
- C49.1Malignant neoplasm of connective and soft tissue of upper limb, including shouldernon-billable header
- C49.2Malignant neoplasm of connective and soft tissue of lower limb, including hipnon-billable header
- C49.3Malignant neoplasm of connective and soft tissue of thorax
- C49.4Malignant neoplasm of connective and soft tissue of abdomen
- C49.5Malignant neoplasm of connective and soft tissue of pelvis
- C49.6Malignant neoplasm of connective and soft tissue of trunk, unspecified
- C49.8Malignant neoplasm of overlapping sites of connective and soft tissue
- C49.9Malignant neoplasm of connective and soft tissue, unspecified
- C49.AGastrointestinal stromal tumornon-billable header
Related codes in this category
- C45Mesotheliomanon-billable header
- C46Kaposi's sarcomanon-billable header
- C47Malignant neoplasm of peripheral nerves and autonomic nervous systemnon-billable header
- C48Malignant neoplasm of retroperitoneum and peritoneumnon-billable header
- C49Malignant neoplasm of other connective and soft tissuenon-billable header