10ICD Code Hub

D75.81

Billable code

Myelofibrosis

The ICD-10 code for myelofibrosis is D75.81.

Clinical notes

Code first

This code represents a manifestation of an underlying disease. Coding convention requires the underlying (etiology) code to be sequenced first, with this code listed second.

  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)

Excludes1 (not coded here)

An Excludes1 note is a pure exclusion: the excluded condition and this code should never be reported together, because the two conditions cannot occur at the same time (e.g. a congenital form vs. an acquired form of the same disease).

  • acute myelofibrosis (C94.4-)
  • idiopathic myelofibrosis (D47.1)
  • leukoerythroblastic anemia (D61.82)
  • myelofibrosis with myeloid metaplasia (D47.4)
  • myelophthisic anemia (D61.82)
  • myelophthisis (D61.82)
  • primary myelofibrosis (D47.1)

Also known as

Alternate wording, synonyms, or specific conditions that fall under this code, listed to help confirm you've picked the right one.

  • Myelofibrosis NOS
  • Secondary myelofibrosis NOS

Use additional code

This code represents an underlying condition. When a related manifestation is also present, coding convention calls for an additional code to be listed after this one.

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Documentation support

General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.

Related codes in this category

ICD-9-CM equivalent

Informational only — GEM mappings are approximate, not guaranteed one-to-one equivalents. Verify before use in billing.

View full ICD-10 → ICD-9 crosswalk →

Associated MS-DRGs

D75.81 can serve as the principal diagnosis for these Medicare Severity Diagnosis-Related Groups.

Informational only — actual DRG assignment also depends on procedures, complications/comorbidities (CC/MCC), discharge status, and payer-specific rules not reflected here.