D81.9
Billable codeCombined immunodeficiency, unspecified
The ICD-10 code for combined immunodeficiency, unspecified is D81.9.
Clinical notes
Also known as
Alternate wording, synonyms, or specific conditions that fall under this code, listed to help confirm you've picked the right one.
- Severe combined immunodeficiency disorder [SCID] NOS
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •This code describes an unspecified presentation. If the medical record documents a more specific detail (e.g. laterality, type, or affected site), a more specific sibling code should be used instead — see Related codes below.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Related codes in this category
- D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.3Adenosine deaminase [ADA] deficiencynon-billable header
- D81.4Nezelof's syndrome
- D81.5Purine nucleoside phosphorylase [PNP] deficiency
- D81.6Major histocompatibility complex class I deficiency
- D81.7Major histocompatibility complex class II deficiency
- D81.8Other combined immunodeficienciesnon-billable header
- D81.9Combined immunodeficiency, unspecified
ICD-9-CM equivalent
Informational only — GEM mappings are approximate, not guaranteed one-to-one equivalents. Verify before use in billing.
- 2792Approximate match
Associated MS-DRGs
D81.9 can serve as the principal diagnosis for these Medicare Severity Diagnosis-Related Groups.
Informational only — actual DRG assignment also depends on procedures, complications/comorbidities (CC/MCC), discharge status, and payer-specific rules not reflected here.
- DRG 808Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC
- DRG 809Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC
- DRG 810Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC