10ICD Code Hub

E22

Header — not billable

Hyperfunction of pituitary gland

The ICD-10 code for hyperfunction of pituitary gland is E22.

E22 is a non-billable header code. It groups related conditions but cannot be used on its own for reimbursement — select one of the 5 more specific codes below.

Clinical notes

Excludes1 (not coded here)

An Excludes1 note is a pure exclusion: the excluded condition and this code should never be reported together, because the two conditions cannot occur at the same time (e.g. a congenital form vs. an acquired form of the same disease).

  • Cushing's syndrome (E24.-)
  • Nelson's syndrome (E24.1)
  • overproduction of ACTH not associated with Cushing's disease (E27.0)
  • overproduction of pituitary ACTH (E24.0)
  • overproduction of thyroid-stimulating hormone (E05.8-)

Documentation support

General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.

Child codes under E22

Related codes in this category