10ICD Code Hub

E34.321

Billable code

Primary insulin-like growth factor-1 (IGF-1) deficiency

The ICD-10 code for primary insulin-like growth factor-1 (igf-1) deficiency is E34.321.

Clinical notes

Also known as

Alternate wording, synonyms, or specific conditions that fall under this code, listed to help confirm you've picked the right one.

  • Acid-labile subunit gene (IGFALS) defect
  • Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
  • Growth hormone insensitivity syndrome (GHIS)
  • Insulin-like growth factor 1 gene (IGF1) defect
  • Laron type short stature
  • Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
  • Signal transducer and activator of transcription 5B gene (STAT5b) defect

Documentation support

General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.

Related codes in this category

Associated MS-DRGs

E34.321 can serve as the principal diagnosis for these Medicare Severity Diagnosis-Related Groups.

Informational only — actual DRG assignment also depends on procedures, complications/comorbidities (CC/MCC), discharge status, and payer-specific rules not reflected here.