10ICD Code Hub

E88.81

Header — not billable

Metabolic syndrome and other insulin resistance

The ICD-10 code for metabolic syndrome and other insulin resistance is E88.81.

E88.81 is a non-billable header code. It groups related conditions but cannot be used on its own for reimbursement — select one of the 4 more specific codes below.

Clinical notes

Use additional code

This code represents an underlying condition. When a related manifestation is also present, coding convention calls for an additional code to be listed after this one.

  • codes for associated manifestations, such as:
  • obesity (E66.-)

Documentation support

General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.

Child codes under E88.81

Related codes in this category

ICD-9-CM equivalent

Informational only — GEM mappings are approximate, not guaranteed one-to-one equivalents. Verify before use in billing.

View full ICD-10 → ICD-9 crosswalk →