O21.1
Billable codeHyperemesis gravidarum with metabolic disturbance
The ICD-10 code for hyperemesis gravidarum with metabolic disturbance is O21.1.
Clinical notes
Also known as
Alternate wording, synonyms, or specific conditions that fall under this code, listed to help confirm you've picked the right one.
- Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as carbohydrate depletion
- Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as dehydration
- Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as electrolyte imbalance
Documentation support
General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.
- •As a general rule, code to the highest level of specificity supported by the documentation in the medical record.
Related codes in this category
- O21.0Mild hyperemesis gravidarum
- O21.2Late vomiting of pregnancy
- O21.8Other vomiting complicating pregnancy
- O21.9Vomiting of pregnancy, unspecified
- O21.1Hyperemesis gravidarum with metabolic disturbance
ICD-9-CM equivalent
Informational only — GEM mappings are approximate, not guaranteed one-to-one equivalents. Verify before use in billing.
- 64313Approximate match
- 64310Approximate match
- 64311Approximate match
Associated MS-DRGs
O21.1 can serve as the principal diagnosis for these Medicare Severity Diagnosis-Related Groups.
Informational only — actual DRG assignment also depends on procedures, complications/comorbidities (CC/MCC), discharge status, and payer-specific rules not reflected here.
- DRG 760Menstrual and Other Female Reproductive System Disorders with CC/MCC
- DRG 761Menstrual and Other Female Reproductive System Disorders without CC/MCC
- DRG 817Other Antepartum Diagnoses with O.R. Procedures with MCC
- DRG 818Other Antepartum Diagnoses with O.R. Procedures with CC
- DRG 819Other Antepartum Diagnoses with O.R. Procedures without CC/MCC
- DRG 831Other Antepartum Diagnoses without O.R. Procedures with MCC
- DRG 832Other Antepartum Diagnoses without O.R. Procedures with CC
- DRG 833Other Antepartum Diagnoses without O.R. Procedures without CC/MCC