10ICD Code Hub

Z79.81

Header — not billable

Long term (current) use of agents affecting estrogen receptors and estrogen levels

The ICD-10 code for long term (current) use of agents affecting estrogen receptors and estrogen levels is Z79.81.

Z79.81 is a non-billable header code. It groups related conditions but cannot be used on its own for reimbursement — select one of the 3 more specific codes below.

Clinical notes

Code first

This code represents a manifestation of an underlying disease. Coding convention requires the underlying (etiology) code to be sequenced first, with this code listed second.

  • , if applicable:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of prostate (C61)

Excludes1 (not coded here)

An Excludes1 note is a pure exclusion: the excluded condition and this code should never be reported together, because the two conditions cannot occur at the same time (e.g. a congenital form vs. an acquired form of the same disease).

  • hormone replacement therapy (Z79.890)

Use additional code

This code represents an underlying condition. When a related manifestation is also present, coding convention calls for an additional code to be listed after this one.

  • code, if applicable, to identify:
  • estrogen receptor positive status (Z17.0)
  • family history of breast cancer (Z80.3)
  • genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
  • personal history of breast cancer (Z85.3)
  • personal history of prostate cancer (Z85.46)
  • postmenopausal status (Z78.0)

Documentation support

General coding-documentation guidance — not a substitute for payer-specific requirements or professional coding judgment.

Child codes under Z79.81

Related codes in this category